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Biopython is vulnerable to doctype XML external entity (XXE) injection through Bio.Entrez — CVE-2025-68463

GitHub · GitHub · CVE-2025-68463

ID
CVE-2025-68463
Date
Updated
Activity
Source
GitHub
Vendor
GitHub
Threat
medium
CVSS
4.9
EPSS
0.00074

Summary

Bio.Entrez in Biopython through 1.86 allows doctype XXE.

Product

pip: biopython

What to do

General, cautious steps (verify details in the official source):

  • Review exposure and plan remediation based on risk and environment.
  • Identify affected product versions in your inventory and verify whether you are impacted.
  • Apply vendor patches/updates or recommended mitigations as soon as available.
  • Read the official advisory for exact affected versions and remediation steps.

Official advisory

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